Vol. 1, Issue 4 (2016)
Zika virus – Outbreaks and epidemiology: A Review Article
Author(s): Shagun Tyagi
Abstract: At present, one of greatest concerns of medical personnel is Zika virus (ZIKV). An outbreak of illness characterized by rash, arthralgia, and conjunctivitis was reported on Yap Island in the Federated States of Micronesia. Serum samples from patients in the acute phase of illness contained RNA of Zika virus (ZIKV), a flavivirus in the same family as yellow fever, dengue, West Nile, and Japanese encephalitis viruses. These findings show that ZIKV has spread outside its usual geographic range. Sixty years earlier, on April 18, 1947, fever developed in a rhesus monkey in the Zika Forest of Uganda. In early 1948, ZIKV was also isolated from Aedes africanus mosquitoes trapped in the same forest. Serologic studies indicated that humans could also be infected. Transmission of ZIKV by artificially fed Ae. aegypti mosquitoes to mice and a monkey in a laboratory was reported in 1956.