Vol. 1, Issue 5 (2016)
Force degradation studies of bioactive berberine and Tinospora cordifolia extract
Author(s): Chanchal Garg, Saurabh Satija, Meenu Mehta, Swati Malik, Munish Garg
Abstract: Since ancient times, herbal medicines have been used by many different cultures throughout the world to treat illness. India has seen immense advancement in herbal drug market, which has resulted in development of infinite therapeutic herbal drug formulations by various manufacturers. With the upgrading of ability in the field of phytochemistry it has now been examined that many of drugs may react with each other increasing the serious task about the stability of such formulations. This is the area, which is essential to address in order to regulate the efficacy of the formulation. Stability testing of herbal products is a challenging job, because the herbal product is observed as the active substance, negligent of whether constituents with defined therapeutic activity are known. The objective of the stability testing is to accommodate evidence of how the property of the herbal products changes with the time under the consequence of environmental factors such as temperature and humidity. Different parameters were analyzed at regular intervals. These studies are regulated at 80°C. The present research work deals with the stability studies by using HPTLC through various stability parameters like alkali hydrolysis, acid hydrolysis, oxidative stress degradation, photolytic degradation and dry heat degradation.