Development and evaluation of sodium alginate-based ketorolac tromethamine floating beads for sustained drug delivery system
Abhiruchi Nevase, Swapnali Zore, Bhaskar Bangar
The study aimed the preparation of floating beads of sodium alginate by using ionotropic gelation method, which is used to prepare sodium alginate floating beads of Ketorolac tromethamine. The influence of various formulation factors such as In vitro drug release, entrapment efficiency, and drug content and floating properties was investigated. The entrapment efficiency were found in range of 60-100 the particle size were found in range of 500-600mm this suggest the ionotropic gelation method was successful in producing sodium alginate floating beads of Ketorolac tromethamine.