International Journal of Research in Pharmacy and Pharmaceutical Sciences

International Journal of Research in Pharmacy and Pharmaceutical Sciences


International Journal of Research in Pharmacy and Pharmaceutical Sciences
International Journal of Research in Pharmacy and Pharmaceutical Sciences
Vol. 4, Issue 3 (2019)

Development and evaluation of sodium alginate-based ketorolac tromethamine floating beads for sustained drug delivery system


Abhiruchi Nevase, Swapnali Zore, Bhaskar Bangar

The study aimed the preparation of floating beads of sodium alginate by using ionotropic gelation method, which is used to prepare sodium alginate floating beads of Ketorolac tromethamine. The influence of various formulation factors such as In vitro drug release, entrapment efficiency, and drug content and floating properties was investigated. The entrapment efficiency were found in range of 60-100 the particle size were found in range of 500-600mm this suggest the ionotropic gelation method was successful in producing sodium alginate floating beads of Ketorolac tromethamine.
Pages : 15-20