International Journal of Research in Pharmacy and Pharmaceutical Sciences

International Journal of Research in Pharmacy and Pharmaceutical Sciences


International Journal of Research in Pharmacy and Pharmaceutical Sciences
International Journal of Research in Pharmacy and Pharmaceutical Sciences
Vol. 4, Issue 3 (2019)

Synthesis and characterisation of pyrazole derivatives from para bromo benzoic acid and its antibacterial activity


Arathi Prakash, Jessy Jacob

Pyrazole is an organic compound with the formula C3H3N2H. It is a heterocycle characterized by a 5-membered ring of three carbon atoms and two adjacent nitrogen atoms. Numerous pyrazole derivatives have been found to possess a broad spectrum of biological activities like anti-bacterial, anti-convulsant, analgesic, anti-microbial, anti-inflammatory, anti-diabetic, sedative anti-rheumatic, anticancer, and anti-tubercular activities. The compounds were synthesized by the normal conventional technique in the lab. All the synthesized compounds were screened for antibacterial activities at three different concentrations (100µg/ml, 250µg/ml, 500µg/ml) against Pseudomonas aeruginosa (Gram –ve) and Bacillus subtilis (Gram + ve) by cup plate agar diffusion method and MIC was found out.
Pages : 40-43