International Journal of Research in Pharmacy and Pharmaceutical Sciences

International Journal of Research in Pharmacy and Pharmaceutical Sciences

ISSN: 2455-698X

Vol. 4, Issue 4 (2019)

Knowledge, awareness about thyroid disorders and detection of adverse drug reaction in thyroid patients

Author(s): Arya O, Shara Abraham, Chinju K Sabu, Sharon Varghese
Abstract: Back Ground: Thyroid disease is one of the most common endocrine disorder. Women make up the majority of thyroid patients and unfortunately, people who have a thyroid problem but are not yet diagnosed make up the majority of thyroid patients. The treatment for thyroid condition depends on the type of thyroid problem and whether the thyroid is overactive, underactive, enlarged, or is cancerous. Methods: A prospective observational cross sectional study was conducted in Nazareth College of pharmacy as a part of thyroid camp organized by Thyrocare, Thiruvalla, Kerala. A questionnaire based study was conducted to collect information on patient demographic, knowledge, awareness, adherence to drug therapy, and adverse drug reaction with respect to hypothyroidism and hyperthyroidism. Result: Out of 110 subject who attended the camp, were classified in to 4 age groups, 41-60 (38%), then age 21-40 are of (35.5%) then below 20 years are of (15.5%) and rest of patients are over 60 years having 11%. Thyroid disease was observed highest in females 73.5% and for males 26.5%, which shows that the prevalence of disorders was significantly higher in females than males. Among the total population31% had thyroid disease (hypothyroidism) while 69% were free from disease, in which 21% were previously diagnosed and 10% were diagnosed at the camp (recently). Family history 35 % remains as the most common risk factor for thyroid disease. Based on the questionnaire the population had poor knowledge regarding thyroid disorders, cause, functions of thyroid gland and symptoms of hypo/hyperthyroidism. Most of them were adhering to their treatment (65%) and the most common causes of non-adherence was found to be the missing of dose. The data obtained from our study confirm that joint pain (17.5%) was the most common adverse drug reaction followed by skin rash (13.04%). Conclusion: The patients with thyroid disorders had a low level of awareness about disease its management and adverse drug reactions. The most common adverse drug reaction identified was joint pain, as levothyroxine can raise uric acid level. Early detection and proper management can further reduce the occurrence of adverse drug reaction associated with medications. The health care providers must also make an endeavour to increase the level of awareness among the patients.
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