Vol. 4, Issue 4 (2019)
Gallic acid: A phyto-phenol role in tumor management with photosensitizing agent as targeting moiety
Author(s): V Sandhiya
Abstract: Gallic acid (3, 4, 5-trihydroxybenzoic acid) a naturally occurring low molecular weight triphenolic compound. which have been used as effectual agent for treating many illnesses from ancient times. In the present scenario the uses of polyphenolic compounds have been widely increased due to its enomorous significant activity and were the commercial drugs are carrying a huge burden of side effects in cancer management. Moreover for complete eradication and to shun resistance by other conventional therapy in tumor cells a novel co-therapy is needed. Recently a co-therapy Photodynamic therapy playing a several role in cancer treatment which has a small number of short term side effects and have high localization on tumor cells. This co-therapy may increase the synergistic effect of polyphenols on tumor cells and use to promote high antioxidant effect on normal cells and also suppose to inhibit angiogenesis process and activate our own immune response toward tumor cells. In future it would be a most promising co-therapy with polyphenols to treat all kind of solid tumors.