International Journal of Research in Pharmacy and Pharmaceutical Sciences

International Journal of Research in Pharmacy and Pharmaceutical Sciences






ISSN: 2455-698X


International Journal of Research in Pharmacy and Pharmaceutical Sciences
International Journal of Research in Pharmacy and Pharmaceutical Sciences
Vol. 5, Issue 5 (2020)

Antioxidant and Antimicrobial activity of Argemone mexicana (Papaveraceae) grown in Sudan


Abdel Karim M, Mustafa I, Faiza I

Argemone mexicana (Papaveraceae) is a herb with various traditional applications around the world. It has several pharmacological activities, among these the anticancer activity. In this study, the GC-MS analysis of Argemone Mexicana oil revealed the presence of 9 components. Major constituents are: oleic Acid, 9, 12-octadecadienoic acid (Z, Z) -, isopropyl linoleate and 9, 12-octadecadienoic acid (Z, Z)-, methyl ester. The oil was evaluated for antimicrobial activity against five standard pathogenic microbes. The antioxidant activity was also assessed. At a concentration of 100mg/ml. the oil showed significant activity against Pseudomonas aeruginosa and moderate activity against Staphylococcus aureus. In the DPPH assay, Argemone mexicana oil showed significant radical scavenging capacity compared to the positive control (propyl gallate).
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