Ayurveda is one of the oldest systems of medicine that uses plants and their extracts for treatment and management of various diseased states. Nyctanthes arbortristis Linn. (NAT) is well known Indian medicinal plant. Phytochemicals like flavanol glycoside, oleanic acid, essential oils, tannic acid, carotene, friedeline, lupeol, glucose, benzoic acid have been reported for significant, hepatoprotective, antileishmaniasis, antiviral, antifungal, antipyretic, antihistaminic, antimalerial, antibacterial, anti-inflammatory, antioxidant activities. Further investigations exploring possible use of these phytochemicals as pharmacological agents are warranted.Each part of the plant has some medicinal value and isthus commercially exploitable. It is now considered as a valuable source of several unique products for the medicines against various diseases and also for the development of some industrial products. The article reviews is an attempt to compile and documented information on different aspect of Nyctanthes arbortristis pharmacological properties and article published on this plant highlighted the need for research and their potential development.