Methods: for in vivo analysis, albino rats were divided into four groups. Control, CuLE (Curry leaf extract) treated, cadmium treated and aqueous extract protected groups. The rats were treated with 6.5 mg/kg body weight cadmium chloride intraperitoneally. And oral route of administration was preferred for curry leaf extract administration.

Results: Increased levels of serum glutamic oxaloacetic transaminase (SGOT) and serum glutamic pyruvic transaminase enzymes (SGPT) were recorded. The level of antioxidant enzymes, Superoxide dismutase and Catalase were also found altered with the exposure of cadmium chloride. All these changes were ameliorative when the rats were treated with curry leaf extract.

Conclusion: Based on the findings we may conclude that aqueous extract of Murraya koenigii can provide complete protection against cadmium chloride toxicity in rats.