Now a day’s Advertisement plays an important role in terms of promotion of any pharmaceutical product as well as influence the choice of consumer. Advertisement must be safe & efficient and should not be misleading and should promote health concern. Thus there must be strict regulations on advertisement. Regulations contain a frame work of advertising including the methods and format of advertising if not appropriate advertisement they have legal actions on it. Regulation in countries like US, Europe, Australia and India improves marketing and create awareness and provides guidelines and law to advertise pharmaceuticals.