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VOL. 3, ISSUE 1 (2018)
A review on chromatographic and spectrophotometric method for estimation of Rosuvastatin calcium and Gemigliptin in synthetic mixture
Authors
Binal J Parekh, Dr. Jignesh S Shah, Dr. Dilip G Maheshwari
Abstract
Gemigliptin is a dpp-4 inhibitor which is use for type 2 diabetes. DPP-4 inhibitors is to increase incretin levels (GLP-1 and GIP), which inhibit glucagon release, which in turn increases insulin secretion and decreases blood glucose level. Rosuvastatin is a HMG-CoA inhibitor, it reduce the cholesterol level. Fixed dose Combination of Gemigliptin and Rosuvastatin showed significant improvement in HbA1C and LDL-C level in T2DM patient with Dyslipidemia and the therapy was well tolerated.
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Pages:71-78
How to cite this article:
Binal J Parekh, Dr. Jignesh S Shah, Dr. Dilip G Maheshwari "A review on chromatographic and spectrophotometric method for estimation of Rosuvastatin calcium and Gemigliptin in synthetic mixture". International Journal of Research in Pharmacy and
Pharmaceutical Sciences, Vol 3, Issue 1, 2018, Pages 71-78
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