ARCHIVES
VOL. 3, ISSUE 1 (2018)
GC-MS analysis and antimicrobial activity of Sudanese Diospyros mespiliformis Hochst. Ex. A. DC. fixed oil
Authors
Abdel Karim M, Balsam O, Mohamed K
Abstract
The present study was aimed to investigate the constituents of Diospyros mespiliformis oil and to evaluate its antimicrobial potency. Diospyros mespiliformis is widely used in Sudanese system of medicine. GC-MS analysis showed the presence of 29 components dominated by: isoproyl linoleate (9, 12-octadecadienoic acid -1-methylethyl ester) - 29.03%; 9, 12-octadecadienoic acid methyl ester (12.10%); 1, 6, 11-dodecatriene (12.02%) and pentadecanoic acid methyl ester (6.68%).
The antimicrobial activity of the oil was assessed against five standard human pathogens (Gram positive: Staphylococcus aureus and Bacillus subtilis; Gram negative: Escherichia coli and Pseudomonasa aeruginosa and the yeast Candida albicans. The oil showed significant activity against Bacillus subtilis. It also exhibited significant anticandidal activity and good activity against other test microorganisms. Hence it is a lead for antimicrobial agents.
Download
Pages:140-143
How to cite this article:
Abdel Karim M, Balsam O, Mohamed K "GC-MS analysis and antimicrobial activity of Sudanese <em>Diospyros mespiliformis</em> Hochst. Ex. A. DC. fixed oil". International Journal of Research in Pharmacy and
Pharmaceutical Sciences, Vol 3, Issue 1, 2018, Pages 140-143
Download Author Certificate
Please enter the email address corresponding to this article submission to download your certificate.