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VOL. 3, ISSUE 2 (2018)
Fast dissolving tablet: An study on novel drug delivery system (A review)
Authors
Shama Parveen, Prabhudutta Panda, Dhaneshwar Kumar Vishwakarma, Jai Narayan Mishra
Abstract
The convenience of administration and improved patient compliance are important in the design of oral drug delivery system which remains the preferred route of drug delivery in spite of various disadvantages. One such problem can be solved in the novel drug delivery system by formulating “mouth dissolving tablets” (MDTs) which disintegrates or dissolves rapidly without water within few seconds in the mouth due to the action of superdisintegrants or maximizing pore structure in the formulation. Fast dissolving tablets are one of them. FDT have benefits such as accurate dosing, easy portability and manufacturing, good physical and chemical stability and an ideal alternative for pediatric and geriatric patients. FDTs have disintegrated quickly, absorb faster so, in vitro drug release time improve and this property of drugs (dosage form) enhanced bioavailability. FDT formulations have the advantage of both conventional tablet formulation and liquid dosage forms. There are several technologies that are conventional or patented based on spray drying, cotton candy process, sublimation, melt granulation, direct compression freezes drying/Lyophilization, phase transition process, mass extrusion, etc. have been developed for manufacturing of FDTs. In this review contain brief information about FDTs including definition, advantages, needs or requirements of FDTs, salient features of FDTs, limitations, marketed formulations of fast dissolving tablets, etc.
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Pages:73-79
How to cite this article:
Shama Parveen, Prabhudutta Panda, Dhaneshwar Kumar Vishwakarma, Jai Narayan Mishra "Fast dissolving tablet: An study on novel drug delivery system (A review)". International Journal of Research in Pharmacy and
Pharmaceutical Sciences, Vol 3, Issue 2, 2018, Pages 73-79
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