The objective of the current study was to develop a simple, sensitive, accurate and precise dual wavelength spectrophotometric method for simultaneous determination of Azilsartan Kamedoxomil and Cilnidipine in combined dosage form. The principle for dual wavelength method is the absorbance difference between two points on the mixture spectra is directly proportional to the concentration of the component of interest. The wavelengths selected for determination of Azilsartan Kamedoxomil are 229.4 nm and 256.9 nm at which Cilnidipine showed same absorbance, whereas the wavelengths selected for determination of Cilnidipine are 238.1 nm and 258.8 nm at which Azilsartan Kamedoxomil showed same absorbance. Methanol is used as a solvent. Regression analysis of Beer’s plots showed good correlation in concentration range of 2-30 μg/ml for Azilsartan Kamedoxomil and 2-25 μg/ml for Cilnidipine. The method was validated according to ICH guidelines for various parameters like linearity, precision (method precision and intermediate precision), accuracy (recovery study), LOD and LOQ. The proposed method is successfully applied for simultaneous estimation of both drugs from synthetic mixture. The assay and recovery results are found satisfactory; hence the method can be applied for the routine QC analysis of both drugs in combination.