Extractive spectrophotometric methods for the determination of Cetirizine using dyes viz., bromocresol green, bromothymol blue and Tropaeolin OO as analytical reagents have been developed and described. The developed methods involved the formation of coloured ion-pair complexes of Cetirizine with dyes in acidic medium. The ion-pair complexes of Cetirizine, with bromocresol green, bromothymol blue and Tropaeolin OO, quantitatively extracted into chloroform, absorbed maximally at 410, 414, and 410nm. The stoichiometry of the complex in three cases is found to be 1:1. The Beer’s law is obeyed in the concentration ranges 2.5-30µg/ml. The effect of concentration of dye, pH and interference of excipients have been studied and optimized. The limits of detection and quantification have been determined for all the three methods. These methods have been validated as per the guidelines of International Conference on Harmonization and have been applied to the determination of Cetirizine in commercial tablets and results of analysis were validated statistically through recovery studies. Thus the newly developed methods are accurate, efficient and stable.