Plants have been used for various medicinal purpose. Ancient people utilized the great diversity of plants. They are source of food, clothing, shelter and medicine. The medicinal use of plants seems to be developed through trial and error method. Many drugs listed as conventional medications were originally derived from plants. Globally, there has been an unparalleled growth in the plant derived medicinal formulations, drugs and healthcare products. The present study of phytochemical, Biochemical and physicochemical analysis of Thespesia polpulnea aims to reveal the presence of various chemical constituents, amound of protein, starch, carbohydrate and nutritional value of the plant.