Abiyamol Moncy, Abiya Susan Shibu, Philip Jacob, Dr. Elessy Abraham
Hyperbaric oxygen therapy (HBOT) is defined as a treatment in which a patient intermittently breathes 100% oxygen while the treatment chamber is pressurized to a pressure greater than sea level (1.0 atmosphere absolute).HBO2 treatment is carried out by using a mono- (single person) or multi-place (typically 2 to 14 patients) chamber. Pressures applied while in the chamber are usually 2 to 3 atmospheres absolute (ATA), the sum of the atmospheric pressure (1 ATA) plus additional hydrostatic pressure equivalent to one or two atmospheres (1 atmosphere = a pressure of 14.7 pounds per square inch or 101 kPa. Hyperbaric oxygen therapy is a new treatment method with a number of different indications. It is managed by different specialities depending up on the need, but most of the hyperbaric facilities are driven by departments of anaesthesiology, and some of the patients are critically ill.Research using a stricter design that includes, random trials, blind experimentation, multiple centers, and large samples are needed for further confirmation. The mechanism of HBOT in the human body is not fully understood still. Further HBOT study using advanced non-invasive techniques, such as Positron Emission Tomography Computed Tomography (PET-CT) and functional Magnetic Resonance Imaging (fMRI) may help to discover additional mechanisms. HBO-PC helps in the reduction of injury to the body in some cases, and its prospects for clinical application as well as the in-depth study of its mechanism will be of broad interest.
Abiyamol Moncy, Abiya Susan Shibu, Philip Jacob, Dr. Elessy Abraham. Hyperbaric oxygen therapy. International Journal of Research in Pharmacy and Pharmaceutical Sciences, Volume 3, Issue 3, 2018, Pages 40-44