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International Journal of
Research in Pharmacy and Pharmaceutical Sciences
ARCHIVES
VOL. 4, ISSUE 2 (2019)
Analgesic activity of various Kariyat extracts in experimental animals
Authors
Kalavati Jambigi, Preeti VK, AR Kulkarni, KJ Hanumanthachar, Injamamul Haque
Abstract
In the present study the various kariyat extracts were used to evaluate analgesic activity in various experimental animal models. Analgesic activity was carried out using acetic acid induced writhing as well as hot plate method in mice. Acute toxicity studies were conducted for the extracts and the test drug doses for screening were selected depending upon LD50 values. Aqueous and ethanolic extracts of kariyat in the dose of 200 & 400 mg/kg b.w, p.o, were used. Aspirin was used as standard for analgesic activity. Kariyat ethanolic extract and Kariyat aqueous extract and aspirin inhibited the writhing significantly (P<0.001) and extracts showed significant activity in hot plate methods by extending time of reaction.
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Pages:26-29
How to cite this article:
Kalavati Jambigi, Preeti VK, AR Kulkarni, KJ Hanumanthachar, Injamamul Haque "Analgesic activity of various Kariyat extracts in experimental animals". International Journal of Research in Pharmacy and Pharmaceutical Sciences, Vol 4, Issue 2, 2019, Pages 26-29
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