Nutraceutical is regarded as the bio active substance and the constituents are either of known therapeutic activity or are chemically defined substance generally accepted to contribute substantially to the therapeutic activity of the drug. Using food products to promote health and cure disease is renowned. Currently, most of the drug molecules available in the formulations were anciently used in their crude form. Dr Stephen De Felice first coins the term nutraceutics in 1989 to provide medical or health benefits including the prevention and treatment of dis-eases. This review classified the large number of nutraceuticals available from various sources and its significance. Further, the regulatory status of nutraceuticals and latest trends in nutragenomics are discussed.