These days various developed and developing countries move towards a combination therapy for treatment of various diseases and disorders requiring long term therapy such as hypertension, Diabetes and Cardiovascular diseases. Over 90% of the formulations, manufactured today are ingested orally. It shows that bilayer tablet formulation is the most popular worldwide and the major attention of the researcher is towards this direction. The major aim of controlled drug delivery is to reduce the frequency of dosing. The design of modified release drug product is to optimize a therapeutic regimen by providing slow and continuous delivery of drug over the entire dosing interval providing greater patient compliance and convenience.