Stroke is one of the leading causes of mortality and disability around the globe. It is also known as cerebrovascular accident or apoplexy. Stroke can be ischemic or hemorrhagic. Established risk factors for stroke are hypertension, diabetes, obesity and physical inactivity. In addition to these traditional cerebrovascular risk factors, infections also become a major risk factor. In stroke patients without traditional risk factors, infections may play a major role particularly in low to middle- income regions. Infectious diseases such as neurosyphilis, neurocysticercosis, tuberculosis, and bacterial meningitis can induce a stroke. Recent reports show that COVID-19 can also increase the risk of stroke. The diagnosis is based on clinical, laboratory, and radiological findings. The burden of stroke is increasing day by day. There-fore infectious causes should be included in the differential diagnosis of stroke. The objective of this study is to review some infectious diseases causing stroke and its management.