All over the world, people are very much concentrating on utilizing an herbal product for their treatment of different diseases since it has less effects and low cost instead of synthetic drugs. The Cardiospermum corindum L. is known as the Love in a puff or Balloon vine plant which is a climber plant which belongs to the family Sapindaceae. The C. corindum L. is broadly developed in the Pantropics regions of Africa, South America and Asia. In north-eastern Brazil, infusion of all parts of C. corindum is used by traditional people to treat liver disease and memory tonic, diuretic, emmenagogue, and rheumatism. In India, the indigenous people of the Karnataka zone are typically utilized the leaf paste of this C. corindum as conventional medicine for the treatment of rheumatoid arthritis, nervous diseases, stiffness of the limbs, and snakebite. This review paper describes the pharmacognostical, geographical, phytochemistry, and pharmacological activity of the C. corindum L. (Sapindaceae). Plants possess phytochemicals constituents such as Tannin, Sterol, Terpenes, Flavonoids, Carbohydrates, Amino acids, Proteins, Saponins, and Alkaloids. Based on various literatures, C. corindum extracts possess various potential pharmacological activities proved by many experimental studies such as Anti-cancer activity, Anti-inflammatory activity, Antioxidant activity, Hepatoprotectivity, Antibacterial Activity and Antispasmodic effect. Henceforth, this plant can be developed as a drug by pharmaceutical industries, based on a numerous study. An overview of C. corindum plant is well described in the present paper.