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VOL. 6, ISSUE 4 (2021)
Evaluation of anti-pyretic activity of Tephrosia purpurea
Authors
E Sankari
Abstract
The aim of the present study is to evaluate the antipyretic activity on methanolic leaves extract of Tephrosia purpurea using yeast induced pyrexia method in albino rats. The fever occurs in patients is mainly due to the body’s immune response is caused by pyrogens (fever producing substances). Pyrogens usually come from a source outside the body and in turn, stimulate the production of pyrogens inside the body. The plant is reported to contain coumarins, falvonoids, carotenoids, flavanones, iso-flavanones and quercetin. The plant has been reported to have anti-pyretic, anti-helmintic, hepato-protective, anti-ulcer, anti-inflammatory, antimicrobial properties. The methanolic leaves extract of Tephrosia Purpurea was investigated for its anti-pyretic activity. Anti pyretic potential of methanolic extract was evaluated by Brewer’s yeast induced pyrexia test. The pyrexia in rats was reduced significantly (P<0.01) when compared to that of control by using standard drug paracetamol.
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Pages:28-30
How to cite this article:
E Sankari "Evaluation of anti-pyretic activity of <em>Tephrosia purpurea</em> ". International Journal of Research in Pharmacy and
Pharmaceutical Sciences, Vol 6, Issue 4, 2021, Pages 28-30
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