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VOL. 8, ISSUE 1 (2023)
Standardization and quality control of herbal medicines derived from pharmaceutical plants
Authors
Dr. Amina Diouf, Kwame Nkrumah, Dr. Ibrahim Toure
Abstract
The growing popularity of herbal medicines necessitates rigorous
standardization and quality control to ensure safety, efficacy, and consistency.
This study focused on evaluating the standardization and quality control of
herbal medicines derived from pharmaceutical plants, specifically Panax
ginseng, Echinacea purpurea, Curcuma longa, Zingiber
officinale, and Withania somnifera. Various analytical methods,
including high-performance liquid chromatography (HPLC), gas chromatography
(GC), mass spectrometry (MS), and DNA barcoding, were employed to determine the
chemical profiles, bioactive compound concentrations, and authenticity of these
herbal products. The study revealed significant variations in the concentration
of key bioactive compounds, such as ginsenosides in ginseng, curcumin in
turmeric, and withanolides in Ashwagandha, with values ranging from 0.8% to
6.5%. Heavy metal contamination (Pb, As, Cd) was found to be negligible in all
samples, and no pesticide residues were detected. Microbial contamination tests
confirmed the absence of pathogens, ensuring safety. The results of DNA
barcoding confirmed the botanical authenticity of all plant species. This study
underscores the importance of comprehensive quality control methods to ensure
that herbal medicines meet the required standards for therapeutic use and
consumer safety.
Pages:43-46
How to cite this article:
Dr. Amina Diouf, Kwame Nkrumah, Dr. Ibrahim Toure "Standardization and quality control of herbal medicines derived from pharmaceutical plants". International Journal of Research in Pharmacy and
Pharmaceutical Sciences, Vol 8, Issue 1, 2023, Pages 43-46
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