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International Journal of
Research in Pharmacy and Pharmaceutical Sciences
ARCHIVES
VOL. 8, ISSUE 2 (2023)
Floating drug delivery system: A review
Authors
Nagendra R, Preethu M N, Venkatesh K, Hanumanthachar Joshi
Abstract
Controlled-release oral delivery systems are programmed to deliver drugs in a predictable time frame. This improves efficacy, minimizes side effects, and increases drug bioavailability. This is the most prevalent route of administration among all routes investigated. Systemic delivery of drugs via pharmaceuticals in different dosage forms. Latest technology and scientific research have been devoted to developing rate-controlled drug delivery systems to Overcome physiological disadvantages such as short gastric residence time and unpredictable stomach time to empty. Inter-subject variability with significant impact on gastric residence time and drug delivery action. This has led to increased interest in formulating new delivery systems. It is retained in the stomach for long, predictable periods. some approaches like floating drug delivery systems (FDDS), swelling and expansion systems, bio adhesive systems, modified Systems, high-density systems, or other devices have been discovered to delay gastric emptying. FDDS is particularly important for locally active drugs with narrow absorption windows. Unstable and low in the gastric or upper small bowel, intestinal, or colonic environment solubility at high pH values. This review article aims to provide detailed information about their design, classification, benefits, pharmacological rationale for in vitro and in vivo evaluation parameters, and the future of FDDS.
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Pages:1-6
How to cite this article:
Nagendra R, Preethu M N, Venkatesh K, Hanumanthachar Joshi "Floating drug delivery system: A review". International Journal of Research in Pharmacy and Pharmaceutical Sciences, Vol 8, Issue 2, 2023, Pages 1-6
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