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VOL. 8, ISSUE 2 (2023)
Sustained release drug delivery systems: A review
Authors
Venkatesh, Mohammed Hasan, Nagendra R, Parthasarathi Kulkarni, Hanumanthachar Joshi
Abstract
The oral route is the most common route for
drug administration, in part because it is simple to use and because
gastrointestinal physiology allows for more design freedom in dosage forms than
most other routes. Drug delivery systems that are intended to produce or
increase therapeutic effect by continually releasing medication over a longer
duration of time upon administration of a single dose are referred to as
long-lasting release, prolonged release, modified release, extended release, or
depot formulations. these dosage types are appealing for a number of reasons: reduces
the variability of peak trough concentration, adverse effects, and frequency of
administration to extend the duration of therapeutic blood levels. It also
increases the bioavailability of the drug product. the most popular and
practical method of drug administration is oral drug delivery because it offers
the most active surface area of any drug delivery mechanism. for internal mode
of treatment, oral drug delivery stays best and the most favored for delivery
for various drugs. Sustained Release can be used to reduce a drug's adverse
effects and boost its therapeutic effectiveness. due to knowledge of drug
toxicity and ineffectiveness when administered orally using the conventional
approach in the form of tablets and capsules, these dosage forms are more
appealing.
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Pages:48-52
How to cite this article:
Venkatesh, Mohammed Hasan, Nagendra R, Parthasarathi Kulkarni, Hanumanthachar Joshi "Sustained release drug delivery systems: A review". International Journal of Research in Pharmacy and
Pharmaceutical Sciences, Vol 8, Issue 2, 2023, Pages 48-52
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