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VOL. 8, ISSUE 4 (2023)
A comprehensive review on buccal drug delivery system
Authors
Prathamesh P Wagh, G V Taware, Yogita D Yewale
Abstract
Buccal drug delivery has
emerged as a promising and innovative approach for administering pharmaceutical
agents, offering advantages such as bypassing hepatic first-pass metabolism,
enhanced patient compliance, and the potential for controlled release. This
research paper provides a thorough and systematic review of the current
state-of-the-art in buccal drug delivery systems, encompassing various aspects
of formulation development and delivery mechanisms. The review begins by
elucidating the anatomical and physiological characteristics of the buccal
mucosa, emphasizing its significance in drug absorption. Key formulation
strategies, including mucoadhesive polymers, permeation enhancers are discussed
in detail, shedding light on their impact on drug bioavailability and
therapeutic efficacy. In conclusion, this comprehensive review provides
valuable insights into the current landscape of buccal drug delivery systems,
offering a roadmap for future research directions and the development of
innovative therapeutic solutions. The integration of multidisciplinary
approaches, collaboration between academia and industry, and a focus on
personalized medicine are emphasized as key factors in advancing the field of
buccal drug delivery.
Pages:37-46
How to cite this article:
Prathamesh P Wagh, G V Taware, Yogita D Yewale "A comprehensive review on buccal drug delivery system". International Journal of Research in Pharmacy and
Pharmaceutical Sciences, Vol 8, Issue 4, 2023, Pages 37-46
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