ARCHIVES
VOL. 8, ISSUE 4 (2023)
Pharmaceutical applications of agricultural microorganisms (Fungi, Bacteria)
Authors
Dr. Elena Kovalenko, Dr. Mateusz Nowak, Dr. Aneta Petrova
Abstract
Agricultural microorganisms, including fungi and bacteria, are valuable
resources for pharmaceutical development due to their ability to produce
diverse bioactive compounds. This study investigated the microbial diversity
and bioactivity of isolates obtained from organic farms, unmanaged soils, and
conventional farms. A total of 120 isolates, including Streptomyces, Bacillus,
Pseudomonas, Aspergillus, and Penicillium, were
identified using morphological and genetic methods. Bioactivity assays revealed
significant antimicrobial activity, particularly from Streptomyces and Aspergillus strains,
with zones of inhibition ranging from 15–30 mm against Staphylococcus
aureus and Escherichia coli. Genomic analysis identified
novel biosynthetic gene clusters, suggesting untapped potential for new drug
discovery. Organic farms exhibited the highest microbial diversity, correlating
with enriched soil organic matter and neutral pH. These findings underscore the
importance of agricultural microorganisms as a sustainable source for
pharmaceutical innovation and the need for further exploration of their
biosynthetic potential.
Pages:49-52
How to cite this article:
Dr. Elena Kovalenko, Dr. Mateusz Nowak, Dr. Aneta Petrova "Pharmaceutical applications of agricultural microorganisms (Fungi, Bacteria)". International Journal of Research in Pharmacy and
Pharmaceutical Sciences, Vol 8, Issue 4, 2023, Pages 49-52
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