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VOL. 9, ISSUE 1 (2024)
In-vitro anti-inflammatory and anti-arthritic activities of hydro-alcoholic extract of berries of Skimmia anquetilia
Authors
Sandeep Goyal, Rakesh Chawla, Faizul Hasan, Vijender Kumar
Abstract
Skimmia anquetilia is
an evergreen, aromatic, monoclinous and perennial shrub. Current investigations
in-vitro anti-inflammatory and anti-arthritic potentials of
berries of Skimmia anquetilia were validated with employing the existing
well developed models i.e. red blood cells membrane stabilization and
protein denaturation methods respectively. Hydro-alcoholic extracts of berries
of S. anquetilia at different concentration levels (50, 100, 200 and 400
mg/ml) were used and dose dependent inhibition effects on protein denaturation
was found 90.11% at 400 mg/ml of extracts and 96.21 % at 100 mg/ml of acetyl
salicylic acid as standard in antiarthritic study. Whereas, in membrane
stabilization method, maximum effect was found as 89.21 % at 400 mg/ml of
extracts and 94.88 % at 100 mg/ml of diclofenac sodium as standard for
anti-inflammatory evaluation. Based on the results outcomes, it is concluded
that, hydro-alcoholic extract of berries of S. anquetilia have shown
significant (*aP<0.05) potential as anti-inflammatory and anti-arthritic
effects.
Pages:76-78
How to cite this article:
Sandeep Goyal, Rakesh Chawla, Faizul Hasan, Vijender Kumar "<i>In-vitro </i>anti-inflammatory<i> </i>and<i> anti</i>-arthritic activities of hydro-alcoholic extract of berries of <i>Skimmia anquetilia</i>". International Journal of Research in Pharmacy and
Pharmaceutical Sciences, Vol 9, Issue 1, 2024, Pages 76-78
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