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VOL. 9, ISSUE 3 (2024)
Nanotechnology-based mucoadhesive drug delivery systems: A comprehensive review
Authors
Ranjita Ramesh Shetty, Vikram T, Gururaj S Kulkarni, Padmaa M Paarakh, Muthukumar A
Abstract
Nanotechnology has the potential to revolutionise medicines through
novel nanodevices. Nanotechnology is the study of matter at sizes ranging from
1 to 100 nm. Mucoadhesives could improve medication delivery systems.
Mucoadhesive polymers could potentially be used to bypass physiological
barriers in long term drug delivery. Nanoparticles are frequently employed due
to their high drug loading capacity, potent stability, controlled release
properties and surface modification for coating and ligand. Mucoadhesive
tablets, pellets, films, sponges, suppositories, beads, wafers and hydrogels
are some of the dosage forms that can improve mucoadhesion. The formulation
base will be choosen based on the anticipated product profile, mode of
administration, active pharmaceutical ingredient and the indication being
treated. The current review article provides an in-depth discussion of several
nanotechnology incorporated drug delivery techniques for improving mucoadhesive
dosage forms that may be intended for buccal, sublingual, vaginal, rectal, nasal
or gastrointestinal administration.
Pages:74-80
How to cite this article:
Ranjita Ramesh Shetty, Vikram T, Gururaj S Kulkarni, Padmaa M Paarakh, Muthukumar A "Nanotechnology-based mucoadhesive drug delivery systems: A comprehensive review". International Journal of Research in Pharmacy and
Pharmaceutical Sciences, Vol 9, Issue 3, 2024, Pages 74-80
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