ARCHIVES
VOL. 9, ISSUE 3 (2024)
Mucoadhesive buccal formulation for anti-migraine agents: A comprehensive review
Authors
Badepalli Reddaiah Reddy, Divya S Kumar, Gururaj S Kulkarni, Padmaa M Paarakh, Muthukumar A
Abstract
The number of migraineurs worldwide has grown dramatically over the
past thirty years, with only considerable differences in incidence rates among
regions and countries. The two primary varieties of migraines are aura-accompanied
and without an aura. Each has peculiar characteristics and causes. The oral
route of administration is the most preferred route for drug delivery, even
though there are several disadvantages, such as enzymatic breakdown and delayed
absorption. Other modes of administration may be employed to provide potential
solutions. In this review, attempts are made at differentiated drug delivery
strategies that need to overcome the limitations of oral administration by
examining mucoadhesive buccal formulations for anti-migraine drugs. The study
presents a comprehensive evaluation of the uses of mucoadhesive buccal
formulations on anti-migraine medications by gathering data from numerous
sources, including research publications. The article analyses mucoadhesive
buccal formulations used in tablets, films, patches, hydrogels, and ointments.
Research samples have also been studied using the mucoadhesive buccal
formulation of several anti-migraine medications, research-evaluated in the
article. The article offers details of specific formulations that have been
researched for various anti-migraine drugs and provides perspective on the
potential of mucoadhesive buccal formulations for effective drug delivery.
Pages:81-87
How to cite this article:
Badepalli Reddaiah Reddy, Divya S Kumar, Gururaj S Kulkarni, Padmaa M Paarakh, Muthukumar A "Mucoadhesive buccal formulation for anti-migraine agents: A comprehensive review". International Journal of Research in Pharmacy and
Pharmaceutical Sciences, Vol 9, Issue 3, 2024, Pages 81-87
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