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International Journal of
Research in Pharmacy and Pharmaceutical Sciences
ARCHIVES
VOL. 9, ISSUE 3 (2024)
Mucoadhesive buccal formulation for anti-migraine agents: A comprehensive review
Authors
Badepalli Reddaiah Reddy, Divya S Kumar, Gururaj S Kulkarni, Padmaa M Paarakh, Muthukumar A
Abstract
The number of migraineurs worldwide has grown dramatically over the past thirty years, with only considerable differences in incidence rates among regions and countries. The two primary varieties of migraines are aura-accompanied and without an aura. Each has peculiar characteristics and causes. The oral route of administration is the most preferred route for drug delivery, even though there are several disadvantages, such as enzymatic breakdown and delayed absorption. Other modes of administration may be employed to provide potential solutions. In this review, attempts are made at differentiated drug delivery strategies that need to overcome the limitations of oral administration by examining mucoadhesive buccal formulations for anti-migraine drugs. The study presents a comprehensive evaluation of the uses of mucoadhesive buccal formulations on anti-migraine medications by gathering data from numerous sources, including research publications. The article analyses mucoadhesive buccal formulations used in tablets, films, patches, hydrogels, and ointments. Research samples have also been studied using the mucoadhesive buccal formulation of several anti-migraine medications, research-evaluated in the article. The article offers details of specific formulations that have been researched for various anti-migraine drugs and provides perspective on the potential of mucoadhesive buccal formulations for effective drug delivery.
Pages:81-87
How to cite this article:
Badepalli Reddaiah Reddy, Divya S Kumar, Gururaj S Kulkarni, Padmaa M Paarakh, Muthukumar A "Mucoadhesive buccal formulation for anti-migraine agents: A comprehensive review". International Journal of Research in Pharmacy and Pharmaceutical Sciences, Vol 9, Issue 3, 2024, Pages 81-87
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