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VOL. 9, ISSUE 4 (2024)
Formulation and in vitro evaluation of topical drug delivery system for emulgel to treat acne
Authors
Siddartha H N, Deepu Gowda Y T, Sumanth A M, Venkatesh, Hanumanthachar Joshi
Abstract
This study presents a novel emulgel formulation combining turmeric and
neem for the topical treatment of acne. Both ingredients are known for their
strong anti-inflammatory, antibacterial, and antioxidant properties, making
them effective against acne-causing bacteria and skin inflammation. By
utilizing an emulgel a hybrid of gel and emulsion the formulation enhances skin
penetration and stability, thus addressing common limitations of traditional
topical acne treatments. Emulgel formulation (F1-F4) was developed using a
concentration of carbopol 940 the formulation assessed their physical-chemical
properties including appearance, pH, spreadability, viscosity, and microscopic
study. Then we conduct a formulation where F3 and F4 have low spreadability and
F1 has less consistency but the F2 formulation passes all the tests and
consistency including pH measurement, viscosity, spreadability, and microscopic
examination. Results showed that the emulgel has a pH level compatible with the
skin, excellent spreadability, and optimal viscosity, making it easy to apply.
Microscopic analysis confirmed the uniform dispersion of active ingredients
within the gel matrix, ensuring even application and absorption.
Pages:46-52
How to cite this article:
Siddartha H N, Deepu Gowda Y T, Sumanth A M, Venkatesh, Hanumanthachar Joshi "Formulation and <i>in vitro</i> evaluation of topical drug delivery system for emulgel to treat acne". International Journal of Research in Pharmacy and
Pharmaceutical Sciences, Vol 9, Issue 4, 2024, Pages 46-52
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