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VOL. 10, ISSUE 1 (2025)
Recent overview on medication for Gestational Diabetes
Authors
Jadhav Bhagyashri A, Shinde Ajay D
Abstract
Gestational diabetes mellitus (GDM) is a
common complication of pregnancy, characterized by glucose intolerance that
develops during gestation. Effective management is crucial to prevent adverse
maternal and fetal outcomes. This review highlights the recent advancements and
current approaches to pharmacological interventions in GDM. Traditionally,
Insulin therapy remains the gold standard for uncontrolled hyperglycaemia due
to its safety profile and efficacy. However, recent studies have explored the
role of Oral Antihyperglycemic agents, such as Metformin and Glyburide, as
alternatives or adjuncts to Insulin therapy. Metformin, despite its placental
transfer, has shown favourable maternal outcomes, although long-term effects on
offspring remain under investigation. Glyburide provides convenience as an oral
agent but may increase neonatal hypoglycaemia risk compared to insulin.
Emerging evidence also suggests the potential for novel agents and personalized
therapy strategies based on genetic and metabolic profiling. This review will
be helps to underscores the need for further clinical investigations to
establish clear guidelines and ensure the safety and efficacy of newer
therapies.
Pages:23-28
How to cite this article:
Jadhav Bhagyashri A, Shinde Ajay D "Recent overview on medication for Gestational Diabetes". International Journal of Research in Pharmacy and
Pharmaceutical Sciences, Vol 10, Issue 1, 2025, Pages 23-28
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