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VOL. 10, ISSUE 3 (2025)
New azo schiff bases compounds and their antibacterial and antifungal activities
Authors
Neelesh Kumar Pandey, Ravi Prakash, R B Singh
Abstract
Ten new azo Schiff bases compounds 5a-h and 7a-b were prepared in
excellent yields via the condensation of different aromatic amines and a new
azoaldehyde, 2-hydroxy-3- methoxy-5-(4-methoxyphenylazo) benzaldehyde (4) by
two different methods. All new compounds were tested against five
microorganisms: Staphylococcus aureus (Gram positive and methicillin
resistant), Bacillus subtilis (Gram positive), Kelebsiella pneumonia,
Pseudomonas aeruginosa and Escherichia coli (all Gram negative).
Compounds 4, 5a, 5c, 5d and 5g were moderately active against Staphylococcus
aureus and Bacillus subtilis. Compound 7b was highly active against Bacillus
subtilis and moderately active against Staphylococcus aureus. Other
compounds were inactive against these strains of bacteria. The antifungal
activities of these compounds were also tested against eight different fungal
species. None of them were active against the fungi species tested.
Pages:6-10
How to cite this article:
Neelesh Kumar Pandey, Ravi Prakash, R B Singh "New azo schiff bases compounds and their antibacterial and antifungal activities". International Journal of Research in Pharmacy and
Pharmaceutical Sciences, Vol 10, Issue 3, 2025, Pages 6-10
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