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International Journal of
Research in Pharmacy and Pharmaceutical Sciences
ARCHIVES
VOL. 10, ISSUE 4 (2025)
Phytochemical analysis and antimicrobial activity of fruit of Detarium microcarpum
Authors
Asim Halfawi Shargi, Mobarak Alsdig, Mohammed Aboied, Ibrahim M E, Fatehalrahman Faris Magbool, Areeg Salih Abdelaziz Ahmed
Abstract
The genus Detarium is indigenous to Africa. In west Africa the genus is represented by eight species, however only three species D.macrocarpum, D.microcarpum and D.senegalense are of ethnomedicinal and pharmacological interest. Detarium species are widely and commonly used in traditional medicine in the treatment of diverse ailments, including, fever, malaria, bronchitis, convulsions, diabetes, microbial infections, etc. the present study was carried out to detect the presence of some phytochemical constituents in the fruit pulp, and to test the antimicrobial activities of n-hexane, chloroform, ethyl acetate and ethanol fruit pulp extract. The GC ∕ MS analysis revealed the presence of the n-hexadecanoic acid, cedarn-diol, (8S, 14)-, (-)-globulol, benzoic acid, (E)- 9-octadecenoic acid,, oleic acid and hexandecanoic acid, methyl ester. The antimicrobial test of the fruit pulp extract showed activity against Pseudomonas aerugenosa, but no activity against Staphylococcus aureus and Aspergillus niger.
Pages:10-14
How to cite this article:
Asim Halfawi Shargi, Mobarak Alsdig, Mohammed Aboied, Ibrahim M E, Fatehalrahman Faris Magbool, Areeg Salih Abdelaziz Ahmed "Phytochemical analysis and antimicrobial activity of fruit of<i> Detarium microcarpum</i>". International Journal of Research in Pharmacy and Pharmaceutical Sciences, Vol 10, Issue 4, 2025, Pages 10-14
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