ARCHIVES
VOL. 10, ISSUE 4 (2025)
A comprehensive review on nanoemulgel formulations for skin disease management
Authors
S Mahalakshmi, Akalyadevi K, Vishalini P, Vijaya P, Mohamed fazil J
Abstract
Skin diseases represent a significant global
health concern, often requiring long-term treatment and patient compliance with
topical drug delivery systems. Conventional topical formulations, however, are
limited by poor drug penetration, instability, and inadequate therapeutic efficacy.
Nanoemulgel formulations have emerged as a promising approach to overcome these
challenges by combining the advantages of nanoemulsions with the favorable
characteristics of hydrogels. These systems enhance drug solubility, stability,
skin permeation, and patient acceptability, thereby improving therapeutic
outcomes in dermatological disorders. This review comprehensively discusses the
fundamental principles of nanoemulgels, their components, methods of
preparation, characterization techniques, and mechanisms of skin penetration.
Furthermore, it highlights recent advancements in the application of
nanoemulgel formulations for the management of various skin diseases, including
infections, inflammation, acne, psoriasis, and cancer. Emphasis is also placed
on regulatory considerations, challenges, and future perspectives in clinical
translation. Overall, nanoemulgel technology offers a versatile and effective
platform for the development of advanced topical therapies in skin disease
management.
Pages:113-117
How to cite this article:
S Mahalakshmi, Akalyadevi K, Vishalini P, Vijaya P, Mohamed fazil J "A comprehensive review on nanoemulgel formulations for skin disease management". International Journal of Research in Pharmacy and
Pharmaceutical Sciences, Vol 10, Issue 4, 2025, Pages 113-117
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