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VOL. 10, ISSUE 4 (2025)
Formulation development in drug product design: A review
Authors
Apeksha P Patil, Deepali K Patil, Supekar Madhuri Vijay
Abstract
Formulation development is a critical phase in the creation of products
across various industries, including pharmaceuticals, cosmetics, food, and
agrochemicals. It involves a systematic and scientific approach to designing
formulations that achieve desired properties, performance, and stability. In
the pharmaceutical and biotechnology sectors, formulation development plays a
key role in determining the success, patentability, and lifecycle of a drug
product. As the demand to accelerate drug discovery and clinical trials grows,
many companies delegate parts of formulation development to specialized teams
or external partners. Large pharmaceutical organizations often establish dedicated
departments for the physical characterization of drug substances and
formulation studies to streamline processes and reduce development timelines.
The concept of pre-formulation, introduced around the 1950s, marked a pivotal
stage in industrial pharmaceutical development. It focuses on understanding the
physicochemical and biopharmaceutical properties of drug substances to design
suitable formulation strategies and delivery methods. Overall, formulation
development bridges the gap between drug discovery and commercialization,
ensuring product efficacy, safety, and stability.
Pages:149-159
How to cite this article:
Apeksha P Patil, Deepali K Patil, Supekar Madhuri Vijay "Formulation development in drug product design: A review". International Journal of Research in Pharmacy and
Pharmaceutical Sciences, Vol 10, Issue 4, 2025, Pages 149-159
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