ARCHIVES
VOL. 11, ISSUE 1 (2026)
Formulation and evaluation of herbal anti-acne cream containing neem, tulsi and Aloe Vera
Authors
Riya Rajpoot, Arpit Jangir, Sunil Kumawat, Santosh Yadav, Chandra Prakash Mishra, Pawan kumar Basniwal
Abstract
Acne vulgaris is a chronic inflammatory disorder of the pilosebaceous
unit commonly affecting adolescents and young adults. Conventional therapies
such as antibiotics, retinoids, and hormonal treatments are effective but may
cause adverse effects, antimicrobial resistance, and skin irritation. Herbal
formulations have gained increasing attention as safer alternatives due to
their antimicrobial, anti-inflammatory, and antioxidant properties. The present
study aimed to formulate and evaluate a herbal anti-acne cream containing
extracts of Azadirachta indica (Neem), Ocimum sanctum (Tulsi), and Aloe
barbadensis (Aloe vera). The cream was prepared using an emulsification
technique with beeswax and liquid paraffin as the base, borax as an emulsifying
agent, and methyl paraben as a preservative. The formulation was evaluated for
physicochemical parameters including pH, spreadability, viscosity, homogeneity,
extrudability, washability, and stability. Antimicrobial activity against
acne-causing microorganisms was also assessed. The prepared cream showed smooth
texture, good spreadability, pH compatible with skin (6.1 ± 0.2), and good
stability under various storage conditions. Antimicrobial testing demonstrated
significant inhibition against acne-causing bacteria. The results suggest that
the herbal anti-acne cream is a safe, stable, and effective formulation with
potential application as a natural alternative for acne management.
Pages:167-169
How to cite this article:
Riya Rajpoot, Arpit Jangir, Sunil Kumawat, Santosh Yadav, Chandra Prakash Mishra, Pawan kumar Basniwal "Formulation and evaluation of herbal anti-acne cream containing neem, tulsi and Aloe Vera". International Journal of Research in Pharmacy and
Pharmaceutical Sciences, Vol 11, Issue 1, 2026, Pages 167-169
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