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VOL. 11, ISSUE 2 (2026)
HR-LCMS-based phytochemical characterization of bark drugs from selected medicinal plants
Authors
S P Kshirsagar, M A Kare
Abstract
Bark drugs constitute an important component of traditional medicine
and are widely used in Ayurvedic, Unani, and folk healthcare systems. The
present investigation aims to evaluate and characterize the phytochemical
composition of bark drugs obtained from selected medicinal plants of the
Marathwada region, Maharashtra, with special emphasis on species belonging to
the genus Ficus. The study integrates pharmacognostic evaluation,
preliminary phytochemical screening, and advanced High-Resolution Liquid Chromatography–Mass
Spectrometry (HR-LCMS) analysis to identify bioactive constituents. Bark
samples of Ficus amplissima, F. arnottiana, F. benjamina, F.
carica, F. elastica, F. hispida, and F. microcarpa
were collected, authenticated, processed, and extracted using suitable
solvents. HR-LCMS profiling revealed the presence of pharmacologically
significant compounds such as quercetin, rutin, kaempferol, gallic acid,
caffeic acid, lupeol, betulinic acid and ursolic acid. The detected
phytoconstituents exhibit antioxidant, anti-inflammatory, antidiabetic,
antimicrobial and hepatoprotective activities, supporting the ethnomedicinal
relevance of these bark drugs. The study establishes chemical fingerprints for
each species and provides scientific validation for their traditional
therapeutic use, contributing to standardization, quality control and future
drug discovery.
Pages:1-4
How to cite this article:
S P Kshirsagar, M A Kare "HR-LCMS-based phytochemical characterization of bark drugs from selected medicinal plants". International Journal of Research in Pharmacy and
Pharmaceutical Sciences, Vol 11, Issue 2, 2026, Pages 1-4
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