Catharanthus roseus linn is a immortal plant. It is identified for its anti- microbial, anti-Oxidant, anti-tumor and anti-mutagenic effect. Catharanthus rosea is an medicinal property belongs to family Apocynaceae. It is cultivated in South Africa, India, U.S.A, Europe & Australia. It is also Cultivated in tropical & Subtropical area / region. Vinca rosea was used for treatment of diabetes in jamaica. The leaves of vinca rosea is green and roots is pale grey in Color. About 90 alkaloids have been isolated from vinca like Ajmalicine, Serpentine are known & present in other species of Apocynaceae. The important alkaloids in Cathranthus are the dimer indole indoline alkoloids vinblastine and Vincristine& they possess anticancer activity. In indole monomeric alkaloids includes Vindoline and Catharanthine. In this review including the pharmacological activity and also morphology, taxonomy. This review is an hard work to collect these chemical constituent, uses, synonyms, cultivation, morphology of vinca is an vast information the literatures on vinca.